brain_138_2toc 1..3

Cover image: Schematic figure showing that transcranial
electrical stimulation of the left posterior parietal lobe
improves left-hand ideomotor apraxia in patients with
left-hemisphere damage. From Bolognini et al. Improving
ideomotor limb apraxia by electrical stimulation of the left
posterior parietal cortex. Pp. 428–439.
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D. M. Kullmann
Scientific Commentaries
When brawn benefits brain: physical activity and Parkinson’s disease risk
C. M. Tanner and C. L. Comella
New hope for the treatment of epilepsy
H. Lerche
Can levodopa-induced dyskinesias go beyond the motor circuit?
J. C. Rothwell and J. A. Obeso
Alterations in structural connectivity may contribute both to the occurrence of tics in Gilles de la Tourette syndrome and
to their subsequent control
A. Draper and S. R. Jackson
Review Article
Pathophysiological concepts in the congenital myopathies: blurring the boundaries, sharpening the focus
G. Ravenscroft, N. G. Laing and C. G. Bo¨nnemann
Physical activity and risk of Parkinson’s disease in the Swedish National March Cohort
F. Yang, Y. Trolle Lagerros, R. Bellocco, H.-O. Adami, F. Fang, N. L. Pedersen and K. Wirdefeldt
Exome sequencing in undiagnosed inherited and sporadic ataxias
A. Pyle, T. Smertenko, D. Bargiela, H. Griffin, J. Duff, M. Appleton, K. Douroudis, G. Pfeffer, M. Santibanez-Koref, G. Eglon, P. Yu-Wai-Man, V. Ramesh,
R. Horvath and P. F. Chinnery
Adult-onset genetic leukoencephalopathies: A MRI pattern-based approach in a comprehensive study of 154 patients
X. Ayrignac, C. Carra-Dalliere, N. Menjot de Champfleur, C. Denier, P. Aubourg, C. Bellesme, G. Castelnovo, J. Pelletier, B. Audoin, E. Kaphan,
J. de Seze, N. Collongues, F. Blanc, J.-B. Chanson, E. Magnin, E. Berger, S. Vukusic, F. Durand-Dubief, J.-P. Camdessanche, M. Cohen, C. Lebrun-Frenay,
D. Brassat, M. Clanet, P. Vermersch, H. Zephir, O. Outteryck, S. Wiertlewski, D.-A. Laplaud, J.-C. Ouallet, B. Brochet, C. Goizet, M. Debouverie,
S. Pittion, G. Edan, V. Deburghgraeve, E. Le Page, C. Verny, P. Amati-Bonneau, D. Bonneau, D. Hannequin, L. Guyant-Mare´chal, N. Derache,
G. Louis Defer, T. Moreau, M. Giroud, A. M. Guennoc, P. Clavelou, F. Taithe, S. Mathis, J.-P. Neau, L. Magy, J. L. Devoize, M. Bataillard,
J. Masliah-Planchon, I. Dorboz, E. Tournier-Lasserve, T. Levade, O. Boespflug Tanguy and P. Labauge
Original Articles
Phenotypic and molecular insights into spinal muscular atrophy due to mutations in BICD2
A. M. Rossor, E. C. Oates, H. K. Salter, Y. Liu, S. M. Murphy, R. Schule, M. A. Gonzalez, M. Scoto, R. Phadke, C. A. Sewry, H. Houlden, A. Jordanova,
I. Tournev, T. Chamova, I. Litvinenko, S. Zuchner, D. N. Herrmann, J. Blake, J. E. Sowden, G. Acsadi, M. L. Rodriguez, M. P. Menezes, N. F. Clarke,
M. Auer Grumbach, S. L. Bullock, F. Muntoni, M. M. Reilly and K. N. North
Significance of neurovascular contact in classical trigeminal neuralgia
S. Maarbjerg, F. Wolfram, A. Gozalov, J. Olesen and L. Bendtsen
L. S. Mendonc¸a, C. No´brega, H. Hirai, B. K. Kaspar and L. Pereira de Almeida
Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model
C. Martins, H. Hu˚lkova´, L. Dridi, V. Dormoy-Raclet, L. Grigoryeva, Y. Choi, A. Langford-Smith, F. L. Wilkinson, K. Ohmi, G. DiCristo, E. Hamel,
J. Ausseil, D. Cheillan, A. Moreau, E. Svobodova´, Z. Ha´jkova´, M. Tesarˇova´, H. Hansı´kova´, B. W. Bigger, M. Hrebı´cek and A. V. Pshezhetsky
Predicting novel histopathological microlesions in human epileptic brain through transcriptional clustering
F. Dachet, S. Bagla, G. Keren-Aviram, A. Morton, K. Balan, L. Saadat, T. Valyi-Nagy, W. Kupsky, F. Song, E. Dratz and J. A. Loeb
Targeting pharmacoresistant epilepsy and epileptogenesis with a dual-purpose antiepileptic drug
A. Doeser, G. Dickhof, M. Reitze, M. Uebachs, C. Schaub, N. M. Pires, M. J. Bonifa´cio, P. Soares-da-Silva and H. Beck
Tract-based spatial statistics to assess the neuroprotective effect of early erythropoietin on white matter development in
preterm infants
R. L. O’Gorman, H. U. Bucher, U. Held, B. M. Koller, P. S. Hu¨ppi, C. F. Hagmann and the Swiss EPO Neuroprotection Trial Group
Pivotal role of choline metabolites in remyelination
T. Skripuletz, A. Manzel, K. Gropengießer, N. Scha¨fer, V. Gudi, V. Singh, L. Salinas Tejedor, S. Jo¨rg, A. Hammer, E. Voss, F. Vulinovic, D. Degen, R. Wolf,
D.-H. Lee, R. Pul, D. Moharregh-Khiabani, W. Baumga¨rtner, R. Gold, R. A. Linker and M. Stangel
A network centred on the inferior frontal cortex is critically involved in levodopa-induced dyskinesias
A. Cerasa, G. Koch, G. Donzuso, G. Mangone, M. Morelli, L. Brusa, M. Stampanoni Bassi, V. Ponzo, S. Picazio, L. Passamonti, M. Salsone, A. Augimeri,
C. Caltagirone and A. Quattrone
Improving ideomotor limb apraxia by electrical stimulation of the left posterior parietal cortex
N. Bolognini, S. Convento, E. Banco, F. Mattioli, L. Tesio and G. Vallar
Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer’s disease
K. Richetin, C. Leclerc, N. Toni, T. Gallopin, S. Pech, L. Roybon and C. Rampon
Why do patients with neurodegenerative frontal syndrome fail to answer: ‘In what way are an orange and a banana alike?’
J. Lagarde, R. Valabre`gue, J.-C. Corvol, B. Garcin, E. Volle, I. Le Ber, M. Vidailhet, B. Dubois and R. Levy
Altered structural connectivity of cortico-striato-pallido-thalamic networks in Gilles de la Tourette syndrome
Y. Worbe, L. Marrakchi-Kacem, S. Lecomte, R. Valabregue, F. Poupon, P. Guevara, A. Tucholka, J.-F. Mangin, M. Vidailhet, S. Lehericy, A. Hartmann
and C. Poupon
Evidence for inhibitory deficits in the prefrontal cortex in schizophrenia
N. Radhu, L. Garcia Dominguez, F. Farzan, M. A. Richter, M. O. Semeralul, R. Chen, P. B. Fitzgerald and Z. J. Daskalakis
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Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph
disease mice
Dorsal Column
Book Reviews
The perplexing conundrum of frontotemporal dementia
J. R. Hodges
From Nissl stains to modern concepts of brainstem function
R. John Leigh
Letters to the Editor
Does dominant pedunculopontine nucleus exist?
S. Lam, E. Moro, Y.-Y. Poon, A. M. Lozano and A. Fasano
Reply: Does dominant pedunculopontine nucleus exist?
B. W. Fling, J. G. Nutt and F. B. Horak
Age-dependent penetrance among females with X-linked adrenoleukodystrophy
M. A. Horn, L. Retterstøl, M. Abdelnoor, O. H. Skjeldal and C. M. E. Tallaksen
Reply: Age-dependent penetrance among females with X-linked adrenoleukodystrophy
M. Engelen, M. Barbier, I. M. E. Dijkstra, R. Schu¨r, R. M. de Bie, C. Verhamme, M. G. W. Dijkgraaf, P. A. Aubourg, R. J. A. Wanders, B. M. van Geel,
M. de Visser, B. T. Poll–The and S. Kemp
TUBB4A novel mutation reinforces the genotype–phenotype correlation of hypomyelination with atrophy of the basal
ganglia and cerebellum
D. Carvalho, S. Santos, B. Martins and F. Pinto Marques
E. M. Hamilton, N. I. Wolf and M. S. van der Knaap
e329, e330, e331, e332
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Reply: TUBB4A novel mutation reinforces the genotype–phenotype correlation of hypomyelination with atrophy of the
basal ganglia and cerebellum